PCBP1 use for generating Stem Cells

The disclosure provides compositions and methods of using gene therapy to create induced pluripotent stem cells (iPSCs) without inducing cancer or tumorigenesis. The methods disclosed herein employ plasmids and vectors that contain transcription factors and an anti-oncogene such as PCBP1 which inhibits the expression of cancer biomarkers and concomitant oncogenesis. WO2021026488A2 - Use of pcbp1 to generate induced pluripotent stem cells while inhibiting oncogenesis - Google Patents

https://patents.google.com/patent/WO2021026488A2/en